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pem disodium  (MedChemExpress)


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    Structured Review

    MedChemExpress pem disodium
    Pem Disodium, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 21 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pem disodium/product/MedChemExpress
    Average 93 stars, based on 21 article reviews
    pem disodium - by Bioz Stars, 2026-02
    93/100 stars

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    Fig. 4. Concentrations of soluble CRT in plasma of NSCLC patients before and after the onset of treatment with cytotoxic agents or osimertinib. (A) The plasma concentration of soluble CRT was determined before (pre), on days 3 and 8 of, and after the end of the first cycle of chemo therapy <t>with</t> <t>DTX</t> (n = 12) or <t>PEM</t> (n = 4) in patients with advanced NSCLC. The maximum (max) value for soluble CRT observed after the onset of treatment was then compared with the corresponding baseline value. **P < 0.01 (Wilcoxon matched-pairs signed-rank test). (B) The plasma concentration of soluble CRT was determined before (pre), on days 3 and 8 of, and about 1 month after the onset of osimertinib therapy in patients with EGFR-mutated advanced NSCLC (n = 9). The maximum (max) value for soluble CRT observed after the onset of treatment was then compared with the cor responding baseline value. ***P < 0.001 (Wil coxon matched-pairs signed-rank test).
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    Fig. 4. Concentrations of soluble CRT in plasma of NSCLC patients before and after the onset of treatment with cytotoxic agents or osimertinib. (A) The plasma concentration of soluble CRT was determined before (pre), on days 3 and 8 of, and after the end of the first cycle of chemo therapy with DTX (n = 12) or PEM (n = 4) in patients with advanced NSCLC. The maximum (max) value for soluble CRT observed after the onset of treatment was then compared with the corresponding baseline value. **P < 0.01 (Wilcoxon matched-pairs signed-rank test). (B) The plasma concentration of soluble CRT was determined before (pre), on days 3 and 8 of, and about 1 month after the onset of osimertinib therapy in patients with EGFR-mutated advanced NSCLC (n = 9). The maximum (max) value for soluble CRT observed after the onset of treatment was then compared with the cor responding baseline value. ***P < 0.001 (Wil coxon matched-pairs signed-rank test).

    Journal: Lung cancer (Amsterdam, Netherlands)

    Article Title: Cytotoxic chemotherapeutic agents and the EGFR-TKI osimertinib induce calreticulin exposure in non-small cell lung cancer.

    doi: 10.1016/j.lungcan.2021.03.018

    Figure Lengend Snippet: Fig. 4. Concentrations of soluble CRT in plasma of NSCLC patients before and after the onset of treatment with cytotoxic agents or osimertinib. (A) The plasma concentration of soluble CRT was determined before (pre), on days 3 and 8 of, and after the end of the first cycle of chemo therapy with DTX (n = 12) or PEM (n = 4) in patients with advanced NSCLC. The maximum (max) value for soluble CRT observed after the onset of treatment was then compared with the corresponding baseline value. **P < 0.01 (Wilcoxon matched-pairs signed-rank test). (B) The plasma concentration of soluble CRT was determined before (pre), on days 3 and 8 of, and about 1 month after the onset of osimertinib therapy in patients with EGFR-mutated advanced NSCLC (n = 9). The maximum (max) value for soluble CRT observed after the onset of treatment was then compared with the cor responding baseline value. ***P < 0.001 (Wil coxon matched-pairs signed-rank test).

    Article Snippet: Pemetrexed disodium (PEM) was obtained from LKT Laboratories; docetaxel (DTX), cisplatin (CDDP), and carboplatin (CBDCA) were from Tocris; gemcitabine (GEM) was from Tronto; and paclitaxel (PTX), vinorelbine ditartrate (VNR), dimethyl sulfoxide were from Wako, and Z-VAD-FMK was from Selleck.

    Techniques: Clinical Proteomics, Concentration Assay